8:00 am Check-In & Coffee
8:50 am Chair’s Opening Remarks
Elevating Real-World Evidence Through Targeted Data Quality Innovation & Governance to Drive Trusted, Actionable Insights
9:00 am Enhancing Trust in Digital RWD by Tackling Attribution & Engagement- Driven Data Quality Issues
Synopsis
- Exploring the unique quality challenges arising from digital health tools, including unclear data attribution and user engagement variability
- Understanding how new RWD sources complicate trust in clinical meaning and the implications for downstream evidence generation
- Discussing solutions such as enhanced metadata tracking, attribution protocols, and user-centric data design to improve reliability
9:30 am Integrating RWE-Derived Counterfactuals into Oncology Trials: Rethinking Crossover Design
Synopsis
- Examine how crossover designs are being increasingly adopted in oncology to provide treatment access while preserving trial integrity
- Explore the use of real-world evidence to construct counterfactual comparisons for patients who switch arms, enabling more robust treatment effect estimation
- Discuss methodological and regulatory considerations for integrating RWE-derived counterfactuals into clinical trial endpoints and analyses
10:00 am Speed Networking
Synopsis
This session is a great opportunity to introduce yourself to the attendees that you would like to
have more in depth conversations with. This session is the ideal opportunity to get face-to-face
time with many of the real-world evidence experts to establish meaningful business relationships.
10:30 am Morning Break
11:00 am Power of Real-World Evidence in Personalized Healthcare in Oncology
Synopsis
- Real-world comparative effectiveness of first-line alectinib versus crizotinib in patients with advanced ALK-positive NSCLC
- Conditional approval of FoundationOne®CDx as a Companion Diagnostic for Rozlytrek® (entrectinib)
- Real-world OS in patients with aNSCLC with KRAS G12C mutation with or without STK11 and/or KEAP1 mutations
Advancing AI & Digital Health Application to Enhance Evidence Generation
11:30 am Machine Learning Meets Real-World Data: Unlocking Better Insights in Healthcare
Synopsis
- Explore how machine learning can be applied to real-world data to predict patient outcomes and uncover hidden patterns in clinical and economic trends
- Assess the potential for ML to complement—or even challenge—traditional health economics methodologies
- Discover how integrating ML into automated insights dashboards can accelerate decision-making and deliver more personalized, scalable healthcare insights
12:00 pm Lunch & Networking Break
1:00 pm Unlocking Precision & Predictive Power with Genetic Data in Real-World Evidence
Synopsis
- Improve patient stratification and treatment targeting by integrating genetic insights into RWE projects
- Enhance the predictive value of real-world studies through deeper biological context and mechanistic understanding
- Navigate data quality, privacy, and integration challenges to maximize the value of genomic data in evidence generation
Navigating Cross-Functional Collaboration to Improve Effectiveness of RWE Studies
1:30 pm Panel: Enhancing Stakeholder Engagement by Communicating RWE Findings in Clear, Purpose-Driven Language
Synopsis
- Demonstrating how to adapt scientific outputs for non-technical audiences including providers, payers, and policy influencers
- Balancing nuance and clarity: ensuring analytical complexity is preserved while maintaining audience accessibility
- Showcasing communication models that increase trust, transparency, and impact of RWE at critical decision points
2:00 pm Afternoon Break & Poster Session
Synopsis
Witness some of the latest and greatest research in the RWE and evidence generation field by
pharma, biotech, and service providers in this spotlight poster session! For more information or to
submit your abstract, please email info@hansonwade.com
3:00 pm Roundtable: Improving Evidence Credibility by Overcoming Emerging Data Quality Challenges
Synopsis
- Examining the persistent impact of poor data quality on value delivery and long-term stakeholder trust in real-world insights
- Identifying common quality pitfalls including missing data, unstandardized reports, and inconsistent integration across traditional sources
- Outlining industry strategies to move from reactive fixes to proactive data governance and quality-by-design approaches
3:30 pm Applying Pragmatic Trial Design to Bridge the Gap Between Research & Practice
Synopsis
- Demonstrating how pragmatic trials generate highly generalizable evidence while preserving scientific rigour
- Identifying when pragmatic design is best suited over traditional RCTs in real-world settings
- Discussing operational considerations including site selection, protocol flexibility, and endpoint relevance